PlexPCR® Technology
Universal DNA/RNA detection platform powering all SpeeDx molecular solutions
PlexPCR® is the proprietary backbone of every SpeeDx assay and the foundation of our multiplexing leadership. Unlike conventional probe-based detection systems with 3-point specificity, PlexPCR® delivers 4-point specificity - providing an extra layer of accuracy that enables confident detection even in challenging multiplex environments.
Our patented PlexZyme® technology and universal probe architecture deliver three critical advantages: accelerated development timelines (compared to industry standard), reduced cost of goods, and ultimate flexibility to detect DNA or RNA targets. This is why leading diagnostic companies including Biocartis and Cepheid have chosen to partner with SpeeDx for their multiplexing needs.
The Science Behind Superior Multiplexing
PlexPCR® uses our patented PlexZyme® technology — a unique signal probe system that enables:
Exceptional Sensitivity
Universal PlexZyme® can detect ≤10 copies of target, with quantitative accuracy across 7+ logs of dynamic range.
Unmatched Specificity
4-point specificity (vs. 3 for competitor systems) provides an additional layer of confidence—critical when multiplexing multiple targets in a single reaction.
Ultimate Flexibility
With probe design independent of the target sequence, these well-characterised universal probes simplify new assay development and reduce reaction and manufacturing cost.
Proven Reliability
Trusted backbone of 50+ commercial products delivering millions of test results annually in laboratories worldwide.
PlexPCR® in Action
This foundational technology powers our entire product portfolio.
STI Testing
Robust multiplexed identification of organisms and drug-resistant markers involved in sexually transmitted infections.
Respiratory Panels
Multiplexed panels that simultaneous detect common seasonal respiratory viruses.
Syndromic Testing
Powering our comprehensive family of gastrointestinal panels that detect common bacteria and parasites with a flexible workflow.
Custom Development
Enabling partners to create bespoke multiplexed assays for specialized applications and emerging pathogens.
Contact the Technology team?
SpeeDx offers the technology, expertise, and partnership models to accelerate your diagnostic success.